Effects of transdermal clonidine (M-5041T) on sleep-wake cycle in rabbits
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چکیده
منابع مشابه
Effects of bilateral lesion of the locus coeruleus on the sleep-wake cycle in the rat
Introduction: Noradrenergic cells in LC participate in the process of cortical activation and behavioral arousal. The evidence suggests that locus ceoruleus (LC) plays an important role in the sleep-wake cycle. The aim of this study was stereological estimation of cavity caused by lesion and assessment of sleep stages after bilateral lesion of the LC. Materials and Methods: Male Wistar rats we...
متن کامل[Sleep-wake cycle mechanisms].
Neurochemically distinct systems interact regulating sleep and wakefulness. Wakefulness is promoted by aminergic, acetylcholinergic brainstem and hypothalamic systems. Each of these arousal systems supports wakefulness and coordinated activity is required for alertness and EEG activation. Neurons in the pons and preoptic area control rapid eye movement and non-rapid eye movement sleep. Mutual i...
متن کاملeffects of bilateral lesion of the locus coeruleus on the sleep-wake cycle in the rat
introduction: noradrenergic cells in lc participate in the process of cortical activation and behavioral arousal. the evidence suggests that locus ceoruleus (lc) plays an important role in the sleep-wake cycle. the aim of this study was stereological estimation of cavity caused by lesion and assessment of sleep stages after bilateral lesion of the lc. materials and methods: male wistar rats wei...
متن کاملEffects of valerian extract on the sleep-wake cycle in sleep-disturbed rats.
The present study was performed to investigate the effects of valerian extract on the sleep-wake cycle using sleep-disturbed model rats. A significant shortening in sleep latency was observed with valerian extract at doses of 1000 and 3000 mg/kg. On the other hand, valerian extract had no significant effects on total times of wakefulness, non-rapid eye movement (non-REM) sleep, or REM sleep, ev...
متن کاملEffects of modafinil and amphetamine on sleep-wake cycle after sleep deprivation in cats.
AIM The effects of modafinil and amphetamine on sleep-wake cycle and cortical power spectrum were assessed in the cats before and after sleep deprivation. METHODS The sleep deprivation in the cats was used with the water tank technique. Cats were administrated with modafinil (5 mg.kg-1 p.o.) or amphetamine (1 mg.kg-1) before and after sleep deprivation. RESULTS The waking effect of 8-10 h i...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1992
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)49466-3